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  1. 2020欧洲杯体育官方网站 Journal

    Pharmacological Reports

    Volume 61 / 2009 - Volume 72 / 2020

  2. 2020欧洲杯体育官方网站 Journal

    Revista Brasileira de Farmacognosia

    Volume 25 / 2015 - Volume 30 / 2020

  3. 2020欧洲杯体育官方网站 Journal

    Therapeutic Innovation & Regulatory Science

    2020欧洲杯体育官方网站Volume 31 / 1997 - Volume 54 / 2020

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    2020欧洲杯体育官方网站 Article

    Radiosynthesis and evaluation of [18F]FMTP, a COX-2 PET ligand

    The upregulation of cyclooxygenase-2 (COX-2) is involved in neuroinflammation associated with many neurological diseases as well as cancers of the brain. Outside the brain, inflammation and COX-2 induction con...

    J. S. Dileep Kumar, Jaya Prabhakaran, Andrei Molotkov in Pharmacological Reports (2020)

  5. Article

    Open Access

    Protective effect of nicotinamide and l-arginine against monocrotaline-induced pulmonary hypertension in rats: gender dependence

    The purpose of this paper was to examine the effects of nicotinamide (ND) and l-arginine (l2020欧洲杯体育官方网站-ARG) on pulmonary vascular and heart changes induced by pulmonary hypertension in rats in a gender-dependent way.

    Katarzyna Sztormowska-Achranowicz, Zbigniew Jankowski in Pharmacological Reports (2020)

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    2020欧洲杯体育官方网站 Article

    Bridging the Gap Between RCTs and RWE Through Endpoint Selection

    This commentary is authored by several industry real-world evidence (RWE) experts, with support from IQVIA, as part of the 'RWE Leadership Forum': a group of Industry Leaders who have come together as non-comp...

    Robert J. LoCasale, Chris L. Pashos in Therapeutic Innovation & Regulatory Science (2020)

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    Article

    Effects of the synthetic cannabinoid XLR-11 on the viability and migration rates of human brain microvascular endothelial cells in a clinically-relevant model

    Synthetic cannabinoids (SCs) are a group of newly-developed drugs that bind and activate endocannabinoid system receptors. Angiogenesis is a biological process in which new blood vessels are formed from preexi...

    Laith AL-Eitan, Ahmed Alhusban, Saif Alahmad in Pharmacological Reports (2020)

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    Article

    Antiallodynic Effect of Piperine in Neuropathic Rats

    2020欧洲杯体育官方网站 Neuropathic pain is a disabling syndrome difficult to manage. Currently, pharmacological treatment of neuropathic patients provides an unsatisfactory relief of pain. Recent reports suggested that piperine has ...

    Luis Arturo Sánchez-Trujillo in Revista Brasileira de Farmacognosia (2020)

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    Article

    Changes of Phenolic Acids and Antioxidant Activities in Diploid and Tetraploid Echinacea purpurea at Different Growth Stages

    Phenolic acids are the main active substances that contribute to the antioxidant activity of Echinacea purpurea (L.) Moench, Asteraceae. However, the effect of chromosome doubling and developmental growth stage o...

    Bai Mei, Huifeng Xie, Huanling Xing, Dexin Kong in Revista Brasileira de Farmacognosia (2020)

  10. Journal

    Archives of Pharmacal Research

    Volume 1 / 1978 - Volume 43 / 2020

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    Article

    A pursuit of Staphylococcus aureus continues: a role of persister cells

    Staphylococcus aureus2020欧洲杯体育官方网站 is a pathogen that causes critical diseases, such as pneumonia, endocarditis, and bacteremia, upon gaining access to the bloodstream of the host. Because host innate immunity alone cannot fi...

    JuOae Chang, Rho-Eun Lee, Wonsik Lee in Archives of Pharmacal Research (2020)

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    Article

    The role of spinally located dopamine D2 receptors in the regulation of the blood glucose level in mice

    The possible role of dopamine D22020欧洲杯体育官方网站 receptors located in the spinal cord in the regulation of the blood glucose level have not been investigated before.

    JaeSeung Hong, JingHui Feng, JinKoo Lee, HeeJung Lee in Pharmacological Reports (2020)

  13. Journal

    Drugs & Therapy Perspectives

    Volume 1 / 1993 - Volume 36 / 2020

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    2020欧洲杯体育官方网站 Article

    Manage acute pain in opioid-tolerant patients with simple analgesics and adjuvants, along with increased doses of opioids if necessary

    2020欧洲杯体育官方网站 Opioid tolerance complicates post-surgical analgesia in many patients, with an increased incidence of psychiatric comorbidity often adding complexity. For the management of acute pain in opioid-tolerant patien...

    Caroline Fenton, Young-A. Heo in Drugs & Therapy Perspectives (2020)

  15. Article

    Knowledge and beliefs towards universal safety precautions during the coronavirus disease (COVID-19) pandemic among the Indian public: a web-based cross-sectional survey

    The novel coronavirus disease 2019 (COVID-19) is considered the most serious global health threat in recent times. As there is a current lack of approved treatments and vaccines, universal safety precautions (...

    Sai Krishna Gudi, Manik Chhabra, Krishna Undela in Drugs & Therapy Perspectives (2020)

  16. 2020欧洲杯体育官方网站 Article

    Open Access

    Biological activity of mistletoe: in vitro and in vivo studies and mechanisms of action

    2020欧洲杯体育官方网站 Mistletoe has been used as treatment of many diseases in traditional and folk medicine. To date, anticancer, immunomodulatory, cardiac, antidiabetic, hepatoprotective, neuropharmacological, antibacterial and a...

    Anna Szurpnicka, Anna Kowalczuk, Arkadiusz Szterk in Archives of Pharmacal Research (2020)

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    2020欧洲杯体育官方网站 Article

    Disulfiram potentiates docetaxel cytotoxicity in breast cancer cells through enhanced ROS and autophagy

    2020欧洲杯体育官方网站 Recent studies have demonstrated that autophagy plays a critical role in reducing the drug sensitivity of docetaxel (DTX) therapy. Disulfiram (DSF) has exhibited potent autophagy inducing activity in multiple ...

    K. Laxmi Swetha, Swati Sharma, Rajdeep Chowdhury, Aniruddha Roy in Pharmacological Reports (2020)

  18. 2020欧洲杯体育官方网站 Article

    Open Access

    Amplifying the Voice of the Patient in Clinical Research: Development of Toolkits for Use in Designing and Conducting Patient-Centered Clinical Studies

    Incorporating patient perspectives into clinical studies is recognized as important to the development of high-quality, safe, and effective fit-for-patient medicines. However, no widely accepted methodology to...

    Mary Elmer MSN, CRNP, Cathy Florek in Therapeutic Innovation & Regulatory Science (2020)

  19. Article

    Open Access

    Use of the Certificate for Pharmaceutical Products (CPP) in 18 Maturing Pharmaceutical Markets: Comparing Agency Guidelines with Company Practice

    The certificate of pharmaceutical product (CPP) was implemented to accelerate the availability of new drugs in developing countries by providing evidence of the quality of products and reducing the time to mar...

    Céline Rodier, Magda Bujar, Neil McAuslane in Therapeutic Innovation & Regulatory Science (2020)

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    Article

    The New Drug Lag: EU Lags in Review Times of Monoclonal Antibodies

    FDA had been criticized for its slow review of new drugs. Critics complained of a “drug lag” from which US patients suffered when compared to Europeans. Since the advent of PDUFA, however, the FDA has demonstr...

    Vibha Sharma, Vivek Dasharath Deore in Therapeutic Innovation & Regulatory Science (2020)

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